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• PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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Mechanistic Assessment of Extrahepatic Contributions to

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

IJMS, Free Full-Text

Frontiers Reviewing Data Integrated for PBPK Model Development

Incorporating Measures of Variability and Uncertainty into the

PDF] In Vitro-In Vivo Extrapolation and Hepatic Clearance

Evidence of the need for modified well-stirred model in vitro to in vivo extrapolation - ScienceDirect

Prediction of hepatic clearance in human from in vitro data for

PDF) Clearance Prediction Methodology Needs Fundamental

Microsomal Stability Assay

Quantitative Prediction of Human Hepatic Clearance for P450 and

Pharmaceuticals, Free Full-Text

PDF) Virtual experiments provide plausible explanations for IVIVE

Precisely adjusting the hepatic clearance of highly extracted

Utilizing virtual experiments to increase understanding of