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TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

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Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain - ScienceDirect

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A cohort of bladder-innervating DRG neurons respond to MRGPR agonists.

TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

Bladder afferent responses to an itch cocktail are absent in

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IJMS, Free Full-Text

TRPV1 is coupled to P2X mediated afferent firing. (a) Peak afferent

PDF) TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

The effect of TRPV1 on urothelial responses to P2X stimulation. (a)